Posts Tagged ‘superoxide’

Elevated plasma superoxide dismutase activity in patients with systemic sclerosis

Thursday, November 12th, 2009

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http://antioxidant-scleroderma.blogspot.com/2009/11/elevated-plasma-superoxide-dismutase.html

By Akimichi Morita and Colleague Injury to vessel walls, especially microvascular damage due to free radicals, has been a focus of interest concerning the pathogenesis of systemic sclerosis. Excess reactive oxygen species may induce antioxidant defenses

Oxidative stress in scleroderma: maintenance of scleroderma fibroblast phenotype by the constitutive up-regulation of reactive oxygen species generati

Thursday, August 6th, 2009

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http://antioxidant-scleroderma.blogspot.com/2009/08/oxidative-stress-in-scleroderma.html

By Sambo P and Colleague OBJECTIVE: To explore the role of reactive oxygen species (ROS) in the in vitro activation of skin fibroblasts from patients with systemic sclerosis (SSc). METHODS: Fibroblasts were obtained from involved skin of patients with limited or diffuse SSc