Posts Tagged ‘patients-with’

Autoantibodies as predictive tools in systemic sclerosis.

Monday, February 8th, 2010

More here:

http://antioxidant-scleroderma.blogspot.com/2010/02/autoantibodies-as-predictive-tools-in.html

Nat Rev Rheumatol. 2010 Feb;6(2):112-6.

Pulmonary arterial hypertension complicating connective tissue diseases

Friday, February 5th, 2010

Read more from the original source:

http://antioxidant-scleroderma.blogspot.com/2010/02/pulmonary-arterial-hypertension.html

Pulmonary arterial hypertension (PAH) may complicate diverse connective tissue diseases (CTDs) such as systemic sclerosis (SSc), systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), and mixed CTD (MCTD) and is an important cause of morbidity and mortality in this context. From a histological standpoint, the pulmonary vascular lesions in PAH complicating CTD are similar to those observed in idiopathic PAH (IPAH).

CT imaging features of pulmonary involvement in connective tissue disorders

Friday, February 5th, 2010

Original post:

http://antioxidant-scleroderma.blogspot.com/2010/02/ct-imaging-features-of-pulmonary.html

Connective tissue disorders correspond to a heterogeneous group of inflammatory diseases characterized by abnormal immune system activity leading to connective tissue alterations in multiple parts of the body. In adults, connective tissue disorders include rheumatoid arthritis, progressive systemic sclerosis, Sjögren syndrome, systemic lupus erythematosus, dermatomyositis and polymyositis, ankylosing spondylitis, and mixed connective tissue disease.

An evaluation of the efficacy of the toe brachial index measuring vascular involvement in systemic sclerosis and other connective tissue diseases.

Friday, February 5th, 2010

Here is the original post:

http://antioxidant-scleroderma.blogspot.com/2010/02/evaluation-of-efficacy-of-toe-brachial.html

OBJECTIVE: The ankle and toe brachial indices (ABI and TBI) are calculated as the ankle and toe systolic blood pressures divided by the highest brachial systolic pressure, respectively. We sought to evaluate the efficacy of ABI and TBI as an objective, non-invasive assessment of vascular involvement in patients with systemic sclerosis (SSc) and to investigate the clinical significance of TBI in SSc. METHODS: ABI and TBI were measured using an oscillometric method in 136 outpatients, including 77 with SSc, 29 with systemic lupus erythematosus (SLE), 16 with primary Sjögren’s syndrome (SjS), and 14 with dermatomyositis (DM)

Determinants of Morbidity and Mortality of Systemic Sclerosis in Canada

Monday, February 1st, 2010

Read more from the original source:

http://antioxidant-scleroderma.blogspot.com/2010/02/determinants-of-morbidity-and-mortality.html

By Firas F.

Correlation of biomarkers of endothelium dysfunction and matrix remodeling in patients with systemic sclerosis.

Monday, January 11th, 2010

View post:

http://antioxidant-scleroderma.blogspot.com/2010/01/correlation-of-biomarkers-of.html

By Blaise S. and Colleague OBJECTIVE: Systemic sclerosis (SSc) is a multisystem disease characterized by microvascular dysfunction and excessive fibrosis. However, the relationship between these 2 features remains unclear

Cooling-induced contraction and protein tyrosine kinase activity of isolated arterioles in secondary Raynaud’s phenomenon.

Thursday, December 24th, 2009

Insightful post at:

http://antioxidant-scleroderma.blogspot.com/2009/12/cooling-induced-contraction-and-protein.html

OBJECTIVE: To investigate the response of skin arterioles from control subjects and patients with scleroderma and Raynaud’s phenomenon (RP/SSc) to cooling and modulators of protein tyrosine kinase (PTK) activity. METHODS: We used the microvessel perfusion technique to characterize the response of isolated dermal arterioles (100-200 microm, outside diameter) from normal (n = 17) and RP/SSc (n = 17) subjects to cooling from 37 degrees to 31 degrees C

Select phytochemicals suppress human T-lymphocytes and mouse splenocytes suggesting their use in autoimmunity and transplantation.

Thursday, December 24th, 2009

Read more here:

http://antioxidant-scleroderma.blogspot.com/2009/12/select-phytochemicals-suppress-human-t.html

By Hushmendy S. and Colleague Nutr Res

Esophageal dysmotility in scleroderma: A prospective study of 183 cases

Monday, December 21st, 2009

View post:

http://antioxidant-scleroderma.blogspot.com/2009/12/esophageal-dysmotility-in-scleroderma.html

Summary Aims The goal of the study was to evaluate the prevalence and risk factors of esophageal motor disorders in systemic sclerosis.

Exhaled nitric oxide, but not serum nitrite and nitrate, is a marker of interstitial lung disease in systemic sclerosis.

Sunday, December 20th, 2009

Great post at:

http://antioxidant-scleroderma.blogspot.com/2009/12/exhaled-nitric-oxide-but-not-serum.html

By Tiev K.P.